• UNIT
    Box
  • Formula

    Bisacodyl ........................................... 5 mg
    Excipients q.s .................................1 tablet

  • Dosage forms

    Enteric film coated tablet.

  • Packing specification

    Box of 4 blisters x 25 enteric film coated tablets.

  • Driving and operating machinery

    No documents have been reported.

  • CAREFUL

    The tablets should not be chewed but swallowed whole. Antacids and milk products should not be given one hour after taking the tablets. Bisacodyl should not be taken on a continuous daily basis for more than one week without asking your physician.

  • PREGNANT AND LACTATING WOMEN

    There are no risks reported when indicated bisacodyl to pregnant women and nursing mothers.

  • DRUG INTERACTIONS

    Prolonged administration or overdose of bisacodyl can reduce the effects of potassium-sparing diuretics or potassium supplements.
    - The concomitant use of bisacodyl and antacids, H2-receptor antagonists or milk products within one hour may reduce the resistance of the coating of the tablets and result in gastric irritation.
    - Bisacodyl reduces the concentrations of digoxin; so it should be taken 2 hours before the ingestion of digoxin.

  • UNWANTED EFFECTS

    Rarely: colic, nausea.
    Inform your physician about any adverse effects occur during the treatment.

  • OVERDOSE AND TREATMENT

    Symptoms: lower abdominal pain accompanied with dehydration, particularly in children and the elderly.
    Treatment: Absorption can be minimised or prevented by inducing vomiting or gastric lavage. Replacement of fluids and monitoring of serum potassium may be required. Administration of antispasmodics may be of value. Correction of electrolyte imbalance is especially important in the elderly and the young.
    There is no specific antidote.

  • STORAGE CONDITIONS

    Store in dry places, not exceeding 30°C, protect from light.

  • Materiality

    Bisacodyl is a locally acting laxative from the triarylmethane group. Bisacodyl stimulates after hydrolysis the mucosa of the large intestine resulting in colonic peristalsis.
    Bisacodyl is hydrolyzed mainly by enzymes of the enteric mucosa to the desacetylbisacodyl, which is absorbed and is partly eliminated in urine and bile as glucuronide. Thanks to bacterial separation, the active ingredient of free diphenol is formed in the large intestine. Bisacodyl coated tablets are formulated to be resistant to gastric and small intestinal juice. This results in a main release of the drug in the colon. After oral administration, only small amounts of the drug are absorbed. Bisacodyl is metabolized in the liver and is eliminated in urine. Following the oral administration of bisacodyl, the elimination was estimated to be approximately 6-8 hours.

  • Expiry
    36 months from the manufacturing date.
  • Indication

    Treatment of constipation. For bowel evacuation before and after surgery. Before taking an X-ray of the colon.

  • Contraindicated

    Bisacodyl should not be used by patients undergoing surgical abdominal conditions, ileus, appendicitis, rectal bleeding, gastroenteritis.
    Hypersensitivity to any components of the drug.

  • DOSAGE AND HOW TO USE

    For the treatment of constipation:
    Adults and children over 10 years: oral dose of 1 - 2 tablets at night. It is advisable to take larger doses (3 or 4 tablets) if required.
    Children aged 6 - 10 years: oral dose of 1 tablet at night.
    For bowel evacuation:
    Adults and children over 10 years: oral dose of 2 tablets at night.
    Children aged 6 - 10 years: oral doe of 1 tablet at night.
    For preparing to take an X-ray of the colon:
    Adults and children over 10 years: oral dose of 2 tablets at night, in two successive nights before taking an X-ray.
    Children aged 6 - 10 years: oral dose of 1 tablet at night, in two successive nights before taking an X-ray.
    Children younger than 6 years of age should not be indicated because the tablet is unable to be divided into small doses.
    Or as directed by the physician.
    Read the directions carefully before use.
    Consult the physician for more information.